I would love to get into the London setting from Cubicle 7, or the Berlin of Wicked City, but familiarity with the New England of the original Lovecraft material means the best locales to explore initially are going to be in and around Arkham. I think once my group are comfortable with the system and their characters' foibles and frailty in the game, I will start to explore some places further afield in the US to begin with. The White Dwarf Hollywood based scenario looks great, and there are still the Keeper's Guide locations to check out. A change of time period will no doubt feel more comfortable after some more experience in the classic setting. It is still early days for me as a keeper so I have yet to grow my confidence with other settings even if I read the scenarios for them voraciously.