For the last year, I have been working on a Malleus Monstrorum-style bestiary dossier for an original eldritch god that I came up with some years ago, with the intent of publishing and selling it on the DriveThru RPG website. One of the ideas I had was for its blood to be mutagenic, transforming the people and creatures exposed to it into more monstrous forms, and I came up with statblocks and commissioned art for mutated versions of humans and several of the more iconic Cthulhu Mythos monsters, namely Deep Ones, Ghouls, Star-Spawn of Cthulhu, and Dark Young; being under the impression that they were in the public domain due to having seen them appear in other non-affiliated media without noticing any accreditation of ownership.
However, I recently discovered that many of the more popular creatures of the Mythos — Yog-Sothoth, Mi-Go, Shoggoths, Elder Things, Star-Spawn, and Dark Young, to name a few — are still under copyright, which has left me with a dilemma: do I rework the parts that may be contentious from a copyright standpoint so that I can still use them (something I've seen some of the aforementioned non-affiliated media do) even if it doesn’t fit what I was going for, or err on the side of caution and completely excise them even if that means the time and money I invested was wasted?
I would like to be able to ask permission to use these elements, but the copyright status of the Cthulhu Mythos is a notoriously convoluted subject so I'm at a total loss as to where to even begin doing so.